This image is a pie chart illustrating the functional classification of the human genome by gene products, meaning it categorizes the expected function of the proteins that all human genes code for. Biochemistry’ is a fundamental health science, but human biochemistry’ is 20,412 genes.
Protein Function Distribution.
The percentages show the relative proportion of genes dedicated to various protein functions.
Unclassified: 23.6%
Transcription factors: 12.0%
Transferases: 8.8%
Nucleic acid binding: 8.5%
Transporters: 6.4%
Receptors: 6.3%
Signaling molecules: 5.6%
Enzyme modulators: 5.0%
Oxidoreductases: 3.2%
Proteases: 2.8%
Cytoskeletal proteins: 2.6%
Hydrolases: 2.6%
Membrane traffic proteins: 1.9%
Structural proteins: 1.6%
Ligases: 1.5%
Transfer/carrier proteins: 1.4%
Phosphatases: 1.3%
Chaperones: 0.8%
Lyases: 0.6%
Defense/immunity proteins: 0.6%
Isomerases: 0.5%
Transmembrane receptor regulatory/adaptor proteins: 0.5%
Cell adhesion molecules: 0.5%
Cell junction proteins: 0.4%
Extracellular matrix proteins: 0.4%
Calcium-binding proteins: 0.4%
Storage proteins: 0.1%
Surfactants: 0.1%
Viral proteins: 0.01%
This type of analysis helps researchers understand the relative importance of different protein functions within an organism’s biology.
