Tag: # Cells.

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Charles Tanford, "The Hydrophobic Effect: Formation of Micelles and Biological Membranes, 2nd Edition, 1980.

Biological Membranes was the subject of an earlier blog post.  Charles Tanford, “The Hydrophobic Effect:  Formation of Micelles and Biological Membranes”, 1st Edition, was published in 1973.  The “Singer-Nicolson” biological membrane model of 1972, generated interest in the “Hydrophobic Effect”.  The “effect” is the strong attraction of water for itself, and weak hydrocarbon attraction. The … Continue reading Charles Tanford, "The Hydrophobic Effect: Formation of Micelles and Biological Membranes, 2nd Edition, 1980.

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S. Singer & G. Nicolson, “The Fluid Mosaic Model of the Structure of Cell Membranes”, SCIENCE, 1972, volume 175, pages 720-731.

The Singer-Nicolson model in biochemistry is second only to the Watson-Crick model in importance. The cell organelles of the two models: 1. cell membranes, and 2. genetic chromosomes are fundamental cellular structures. In the diagram above, proteins are large objects in the lipid fluid. The years 1953 and 1972 gave biochemistry these new idea models. Continue reading S. Singer & G. Nicolson, “The Fluid Mosaic Model of the Structure of Cell Membranes”, SCIENCE, 1972, volume 175, pages 720-731.

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Joseph Katz, "The use of Glucose Carbon-14 in the Study of the Pathways of Glucose Metabolism in Mammalian Tissues".

Here is the use of a radioactive isotope in metabolomics by Joseph Katz.  Otto Warburg’s decades earlier research  was foundational metabolism study.  Carbon-14, here used by Joseph Katz was the next generation of metabolomics. Continue reading Joseph Katz, "The use of Glucose Carbon-14 in the Study of the Pathways of Glucose Metabolism in Mammalian Tissues".