
Here I present: “Hereditary Congenital Facial Paresis”, Victor McKusick, Mendelian Inheritance in Man’, 1966. 莫比乌斯综合症。(HCFP).
INTRODUCTION.
Hereditary congenital facial paresis (HCFP) is the isolated dysfunction of the facial nerve (CN# 7). HCFP is a neurological disorder presumed to result from maldevelopment of the facial nucleus and/or cranial nerve. It is a disorder also called Moebius syndrome type-2 (MBS2).
There is evidence hereditary congenital facial paresis type-1 is caused by mutation in the HCFP1 gene encoded on cytogenetic location 3q21-q22 and genomic coordinates 3:122,200,001-139,000,000. The screenshot of the HCFP1 gene 16,800,000 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides HCFP1 in the 3q21-q31 cytogenetic location are listed BENEATH. 


| Coordinate | Symbol | Genomic Name |
| 3:122,200,001 | ATOD1 | Dermatitis, atopic, 1 |
| 3:122,200,001 | ERVK-4 | Endogenous retrovirus K, member 4 |
| 3:122,200,001 | FGQTL6 | Fasting plasma glucose level QTL 6 |
| 3:122,200,001 | GLC1C | Glaucoma 1, open angle, C |
| 3:122,200,001 | HCFP1 | Facial paresis, hereditary congenital |
| 3:122,200,001 | PSORS5 | Psoriasis susceptibility 5 |
| 3:122,325,248 | CSTA | Cystatin A (stefin A) |
| 3:122,359,591 | MIX23 | Mitochondrial matrix import factor 23 |
| 3:122,384,182 | FAM162A | Family with sequence 162, member A |
| 3:122,421,902 | KPNA1 | Karyopherin, alpha-1 |

