V Bloomfield, D Crothers, I Tinoco, “Physical Chemistry of Nucleic Acids”, 1974. 核酸的物理化学。核酸の物理化学。

INTRODUCTION.

V Bloomfield, D Crothers, I Tinoco, “Physical Chemistry of Nucleic Acids”, 1974 was a monograph by experts in three (3) different areas: Spectroscopy, Thermodynamics, Chemical Binding. Each of the three (3) authors wrote chapters in his area of expertise. Beginning with the “Genetic Code” (shown BELOW) each author presented chapters useful for advanced students.

COMMENTS.

“Nucleic Acids Thermodynamics” (Wikipedia hyperlink) is a good supplement to V Bloomfield, D Crothers & I Tinoco, “Physical Chemisty of Nucleic Acids, 1974.  For example, the DNA base pairs sequences  (shown BELOW) Thermodynamics is very clear in the article.      BENEATH is a schematic diagram of the twenty-four (24) nuclear chromosomes (22,XY) from a Chemical Thermodynamic viewpoint used in Molecular Cell Biology.

Sequence

(5′-3’/3′-5′)

AA/TT

AT/TA

TA/AT

CA/GT

GT/CA

CT/GA

GA/CT

CG/GC

GC/CG

GG/CC

Terminal A/T

Terminal G/C