Genomic coordinate (human 10:51,100,001 ALL1).
Cytoband (human 10q21.1 ALL1).
Here I present: “Acute Lymphoblastic Leukemia Susceptibility”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (ALL1) 急性淋巴細胞白血病易感性 icd10=C91.0
INTRODUCTION
Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a subtype of acute leukemia, a cancer of the white blood cells. Somatically acquired mutations in several genes have been identified in ALL lymphoblasts, cells in the early stages of differentiation. Germline variation in certain genes may also predispose to susceptibility to ALL.
A susceptibility locus for acute lymphoblastic leukemia (ALL1) has been mapped to cytoband 10q21.1 at genomic coordinate 10:51,100,001.
