ABOVE is the twenty-four (24) hour day of CHROMOSOMIC CLOCK and this time is one (#1).
Here I present: “Cutaneous Malignant Melanoma (dysplasia-nevus)”, Victor McKusick, Mendelian Inheritance in Man’, 1966. The photograph ABOVE is shown to make three (3) diagnostic distinctions: melanoma, common-nevi & dysplasia-nevi.
INTRODUCTION.
Examination of the melanoma skin cancer shows A.B.C.D.E. Theses malignant melanoma signs are: Asymmetry, Border, Color, Diameter, Evolution.
- Asymmetry – Melanoma is often asymmetrical, which means the shape isn’t uniform. Non-cancerous moles are typically uniform and symmetrical in shape.
- Border – Melanoma often has borders that aren’t well defined or are irregular in shape, whereas non-cancerous moles usually have smooth, well-defined borders.
- Color – Melanoma lesions are often more than one color or shade. Moles that are benign are typically one color.
- Diameter – Melanoma growths are normally larger than 6mm in diameter, which is about the diameter of a standard pencil.
- Evolution – Melanoma will often change characteristics, such as size, shape or color. Unlike most benign moles, melanoma tends to change over time. If you have a mole or skin growth, watch it for signs of changes.
Cutaneous malignant melanoma (CMM1) is on cytogenetic location 1p36 and genomic coordinates 1:1-27,600,000 . The screenshot of the gene is shown BELOW of CMM1 of 27,600,000 bp (base pairs) of DNA sequence length.
