


Here I present: “Dilated Cardiomyopathy”, Victor McKusick, Mendelian Inheritance in Man’, 1966.
INTRODUCTION.
Dilated cardiomyopathy (DCM) is a condition in which the heart becomes enlarged and cannot pump blood effectively. Symptoms vary from none to feeling tired, leg swelling, and shortness of breath. It may also result in chest pain or fainting. Complications can include heart failure, heart valve disease, or an irregular heartbeat. Dilated cardiomyopathy-1A (CMD1A) is caused by heterozygous mutation in the lamin A/C gene (LMNA) on cytogenetic location 1q22 and genomic coordinates 1:156,082,573-156,140,081 . The screenshot of the lamin A/C gene (LMNA) is shown BELOW of the 57,509 bp (base pairs) of DNA length. 



