ICD10 code = C91.1
Genomic coordinate (human 13:49,912,705 DLEU2).
Cytoband (human 13q14.2 DLEU2).
OMIM’ genes @ 13q14.2 = 18 genes.
ClinVar = 5 DLEU2 variants reported.
PANTHER Classification of DLEU2 is “Non-protein Coding” (Unclassified).
Here I present: “Chronic B-cell Lymphocytic Leukemia”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (DLEU2)
INTRODUCTION.
Chronic B-cell Lymphocytic Leukemia (CLL) is a type of slow-growing blood and bone marrow cancer where abnormal B-lymphocytes multiply and crowd out healthy blood cells.
Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. In CLL, the bone marrow produces too many lymphocytes, which are a type of white blood cell. B-cell lymphocytes can begin to collect in the blood, spleen, lymph nodes, and bone marrow; these cells malfunction and crowd out healthy blood cells. CLL is divided into slow-growing (indolent) and fast-growing variants.
