Here I present: “TRITANOPIA: Blue Colorblindness”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (OPN1SW) 三色藍色盲。icd10=H53.55
INTRODUCTION.
Tritanopia is an autosomal dominant disorder of human vision characterized by a selective deficiency (color blindness) of blue vision.
There is evidence tritanopia is caused by heterozygous mutation in the blue cone pigment (OPN1SW) gene on cytogenetic location 7q32.1 and genomic coordinates 7:128,772,485-128,775,794. The screenshot of the OPNISW gene 3,310 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes OPNISW in the 7q32.1 cytogenetic location are listed BENEATH.
| Coordinate | Symbol | Genomic Name |
| 7:128,476,748 | METTL2B | Methyltransferase 2B, methylcytidine |
| 7:128,671,629 | GARIN1A | Golgi-associated Rab2 interactor 1A |
| 7:128,709,061 | GARIN1B | Golgi-associated Rab2 interactor 1B |
| 7:128,739,359 | CALU | Calumenin |
| 7:128,772,485 | OPN1SW | Blue cone pigment |
| 7:128,790,761 | CCDC136 | Coiled-coil domain-containing protein 136 |
| 7:128,830,406 | FLNC | Filamin C (actin-binding protein-280) |
| 7:128,862,856 | ATP6V1F | ATPase, H+ transporting, lysosomal, 14kD, V1 subunit F |
| 7:128,876,865 | KCP | Kielin/chordin-like protein |
| 7:128,937,032 | IRF5 | Interferon regulatory factor 5 |
