

Here I present: “Feingold Syndrome”, Victor McKusick, Mendelian Inheritance in Man’, 1966. 眼指食管十二指肠综合征。
INTRODUCTION.
Feingold syndrome (also called oculodigitoesophagoduodenal syndrome) is a autosomal dominant hereditary disorder. It is named after Murray Feingold, an American physician who first described the syndrome in 1975.
Feingold syndrome is marked by various combinations of microcephaly, limb malformations, esophageal atresia and duodenal atresia. Cognition is affected, and ranges from below-average IQ to mild intellectual disability.
Feingold syndrome is caused by mutations in the neuroblastoma-derived V-myc viral-related oncogene (MYCN) which is located on cytogenetic location 2p24.3 and genomic coordinates 2:15,940,550-15,947,004 . The screenshot of the MYCN gene 6,455 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides MYCN in the 2p24.3 cytogenetic location are listed BENEATH. 


| Coordinate | Symbol | Genomic Name. |
| 2:14,778,909 | NBAS | NBAS subunit of NRZ tethering complex |
| 2:15,591,868 | DDX1 | DEAD-box helicase 1 |
| 2:15,920,399 | MYCNUT | MYCN upstream transcript, noncoding |
| 2:15,936,265 | MYCNOS | Oncogene NCYM, opposite strand |
| 2:15,940,550 | MYCN | Oncogene NMYC |
| 2:16,050,427 | GACAT3 | Gastric cancer-associated transcript 3, noncoding |
| 2:17,539,972 | VSNL1 | Visinin-like 1 |
| 2:17,663,812 | SMC6L1 | Structural maintenance of chromosomes 6-like 1 |
| 2:17,753,278 | GEN1 | GEN1 Holliday junction 5′ flap endonuclease |
| 2:17,816,460 | MSGN1 | Mesogenin 1 |

