Here I present: “Schnyder Crystalline-Corneal Dystrophy”, Victor McKusick, Mendelian Inheritance in Man’, 1966.
INTRODUCTION.
Schnyder Crystalline-Corneal Dystrophy (SCCD) is a corneal dystrophy. It is caused by heterozygous mutations in UBIAD1 gene. Cells in the cornea accumulate cholesterol and phospholipid deposits leading to the opacity, in severe cases requiring corneal transplants. Abnormal cholesterol metabolism has been noted in other cell types of affected patients (skin fibroblasts) suggesting that this may be a systemic disorder with clinical manifestations limited to the cornea.
There is evidence that Schnyder corneal dystrophy (SCCD) is caused by heterozygous mutation in the UBAID1 gene on cytogenetic location 1p36.22 and genomic coordinates 1:11,273,198-11,299,574 . The screenshot of the UBAID1 gene 26,377 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides UBAID1 in the 1p36.22 cytogenetic location are listed BENEATH. 
| Coordinate | Symbol | Genomic Name. |
| 1:11,054,589 | SRM | Spermidine synthase-1 |
| 1:11,066,618 | EXOSC10 | Exosome component 10 |
| 1:11,106,535 | MTOR | Mechanistic target of rapamycin |
| 1:11,189,355 | ANGPTL7 | Angiopoietin-like 7 |
| 1:11,273,198 | UBIAD1 | UbiA prenyltransferase domain protein |
| 1:11,479,155 | DISP3 | Dispatched RND transporter family, 3 |
| 1:11,648,387 | FBXO2 | F-box protein 2 |
| 1:11,654,407 | FBXO44 | F-box protein 44 |
| 1:11,664,200 | FBXO6 | F-box protein 6 |
| 1:11,674,480 | MAD2L2 | Mitotic arrest-deficient 2 like 2 |
