Marina Seabright, “Rapid Banding Technique for Human Chromosomes”, 1971 was the topic of an earlier blog post.
Here I present: Marina Seabright, Rapid Banding Technique for Human Chromosomes’ , 1971, PART TWO (II). Definition of the term “molecule” changed because of “molecular biology”.
INTRODUCTION.
Binding to chromosomal DNA occurs by five (5) modes; however, only one of the modes “intercalates” inside double-strand DNA (shown ABOVE). Giemsa intercalates and produces chromosomal DNA banding. The “banding” is of five intensity levels of Giemsa stained chromosomes:
#1. Black band DNA.
#2. Dark-Gray band DNA.
#3. Gray band DNA.
#4. Light-Gray band DNA.
#5. White band DNA.
This pattern of banding is shown for gender chromosomes BELOW. #X and #Y chromosomes consist of intact DNA molecules, that can be seen under the microscope using Marina Seabrigth’s stain.
Here I presented: Marina Seabright, Rapid Banding Technique for Human Chromosomes’ , 1971, PART TWO (II). The definition of the term “molecule” changed because of “molecular biology”.
COMMENTS.
Chromosomal DNA are molecules occurring. The DNA molecules are not “phase molecules” in the sense of solid, liquid, vapor phases.
DNA molecules are however, “elemental molecules” in sense of the universal periodic elements’ (table shown BELOW). Marina Seabright, “Rapid Banding Technique for Human Chromosomes”, 1971 is “periodicity” for biochemistry’.
Dmitri Mendeleev was the inorganic chemist of “periodicity” for the table shown BENEATH. “Periodicity” is in the today sense coined by the term “genome”. ABOVE are the chromosomes arranged in clockwork circularity to imply the today definition of “molecule”, and not the historic concept of inorganic chemist Dmitri Mendeleev. Marina Seabright was a biochemist, and we use her notation today for chromosomal DNA molecules that is modern biochemistry’.
