Antoine Lavoisier, ”Elements of Chemistry “, 1789 marks the beginning of modern chemistry. The first list of the periodic chemical elements is in this book. The nomenclature is however what was foundational. The “SMILES” notation is a recent advance in the Computer Age, that cab be traced to this publication by Lavoisier in 1789. “SMILES” is the Simplified Molecular Identity Line Entry System standardization today, as Lavoisier’s standardization was in 1789.