Victor McKusick, “Mendelian Inheritance in Man”, 1966 was the topic of an earlier blog post.
Here I present: 20,412 as my reference number for the encoded in the Human Genome.
The reference number that I use for the number of Human proteins is 20,412.
Long before the Human Genome Project came into existence geneticists estimated the number (order of magnitude) to be about 10,000 proteins. This is a value from 1966 when Victor McKusick, “Mendelian Inheritance in Man”, 1966 was first published.
Here I presented: 20,412 proteins in the Human Genome today. The ABOVE pie-chart shows the distribution of proteins in various classes now known. Today, all 20,412 proteins have been observed and named.
However, in 1966 only an estimate of the number Human proteins existed as over 10,000. Every, protein today is being classified .
The chart shows 23.6% of the 20,412 proteins 4,061 are still unclassified.