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V Bloomfield, D Crothers, I Tinoco, “Physical Chemistry of Nucleic Acids”, 1974. 核酸の物理化学。PART TWO (2).

Phoebus Levene (1869-1940), “Uber die Hefenucleinsaure (About the Yeast Nucleic Acid”, 1909 was the topic of an earlier blog post.

Here I present: V Bloomfield, D Crothers, I Tinoco, “Physical Chemistry of Nucleic Acids”, 1974. PART TWO (2). 核酸の物理化学。

INTRODUCTION.

Bloomfield-Crothers-Tinoco, 1974 is a good source for DNA history.  DNA was believed to be an organic molecule of molecular formula C39H51O25N15P4 according to 1909 study by Phoebus Levene.   X-ray crystallography of DNA in 1952 provided evidence for not accepting the Phoebus Levene viewpoint.  Other DNA structures are listed BELOW, including the 1953 B-DNA model Watson-Crick.

A-DNA: 11 base turn molecules.

B-DNA: 10 base turn (Watson-Crick).

C-DNA: 9.3 base turn molecules.

D-DNA: 8 base turn molecules.

Z-DNA: turn is left-handed.

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