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“Chromosome #7 Short-Arm”, Victor McKusick, Mendelian Inheritance in Man, 1966.

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Hyperreflexia”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (HRX) 反射亢進。icd10=R29.2  was the topic of an earlier blog post.

Here I present: “Chromosome #7 Short-Arm”, Victor McKusick, Mendelian Inheritance in Man’, 1966.

INTRODUCTION. 

Chromosome #7 has popular, commonly discussed items shown ATOP.  If you open the image as GOOGLE search, then select the TEXT, the playback from READALOUD is useful for learning chromosome #7 genes ATOP.

Hyperreflexia (HRX) at genomic coordinate 7:60,100,001 is located at the centromere division of long-and-short arms of chromosome #7.  Victor McKusick, Mendelian Inheritance in Man’, 1966 is the source of the three-hundred-three (303) genes listed BELOW of chromosome #7 short-arm.

 

 

Coordinate  Symbol  Genomic Name
7:1.. ERVK-6 Endogenous retroviral group K, member 6
7:1.. HYPT10 Hypotrichosis 10
7:192,571  FAM20C Family with sequence similarity 20, member C
7:497,258  PDGFA Platelet-derived growth factor, alpha polypeptide
7:549,197  PRKAR1B Protein kinase, cAMP-dependent, regulatory, type I, beta
7:726,699  DNAAF5 Dynein axonemal assembly factor 5
7:815,557  SUN1 SAD1 and UNC84 domain-containing protein 1
7:876,554  GET4 Guided entry of tail-anchored proteins factor 4
7:897,900  ADAP1 ARFGAP with dual pleckstrin homology domains 1
7:964,852  COX19 Cytochrome c oxidase assembly protein Cox19
7:977,964  CHLSN Cholesin
7:983,181  CYP2W1 Cytochrome P450, family 2, subfamily W, polypeptide 1
7:1,022,933  MIR339 Micro RNA 339
7:1,044,546  GPR146 G protein-coupled receptor 146
7:1,087,118  GPER1 G protein-coupled estrogen receptor 1
7:1,148,850  ZFAND2A Zinc finger AN1 domain-containing protein 2A
7:1,434,359  MICALL2 MICAL-like protein 2
7:1,470,277  INTS1 Integrator complex subunit 1
7:1,530,702  MAFK MAF bZIP transcription factor K
7:1,567,332  PSMG3 Proteasome assembly chaperone 3
7:1,666,064  ELFN1 Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 1
7:1,815,795  MAD1L1 Mitotic arrest-deficient 1, yeast, homolog-like 1
7:2,234,195  MRM2 Mitochondrial ribosomal RNA methyltransferase 2
7:2,242,226  NUDT1 Nudix hydrolase 1
7:2,251,770  SNX8 Sorting nexin 8
7:2,354,086  EIF3B Eukaryotic translation initiation factor 3, subunit B
7:2,403,448  CHST12 Carbohydrate sulfotransferase 12
7:2,474,728  GRIFIN Galectin-related interfiber protein
7:2,512,529  LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
7:2,537,810  BRAT1 BRCA1-associated ATM activator 1
7:2,558,979  IQCE IQ domain-containing protein E
7:2,631,986  TTYH3 Tweety family member 3
7:2,679,522  AMZ1 Archaelysin family metallopeptidase 1
7:2,728,105  GNA12 Guanine nucleotide-binding protein, alpha-12
7:2,906,142  CARD11 Caspase recruitment domain-containing protein 11
7:3,301,252  SDK1 Sidekick cell adhesion molecule 1
7:4,500,001  STBMS1 Strabismus, susceptibility to, 1
7:4,682,295  FOXK1 Forkhead box K1
7:4,775,623  AP5Z1 Adaptor-related protein complex 5, zeta-1 subunit
7:4,797,055  RADIL RAP GTPase interactor
7:4,857,738  PAPOLB Poly(A) polymerase, beta
7:4,892,245  MMD2 Monocyte-to-macrophage differentiation-associated protein 2
7:5,045,860  RBAK RB-associated KRAB zinc finger
7:5,190,233  WIPI2 WD40 repeat protein interacting with phosphoinositides 2
7:5,282,943  SLC29A4 Solute carrier family 29 (monoamine transporter), member 4
7:5,306,811  TNRC18 Trinucleotide repeat-containing gene 18
7:5,454,425  FBXL18 F-box and leucine-rich repeat protein 18
7:5,527,148  ACTB Actin, beta
7:5,592,816  FSCN1 Fascin homolog 1, actin-bundling protein (singed, Drosophila, homolog-like)
7:5,620,047  RNF216 RING finger protein 216
7:5,859,718  OCM Oncomodulin
7:5,898,733  CCZ1 CCZ1 homolog, vacuolar protein trafficking- and biogenesis-associated protein
7:5,970,925  PMS2 PMS1 homolog 2, mismatch repair system component
7:6,009,272  AIMP2 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
7:6,022,247  EIF2AK1 Eukaryotic translation initiation factor 2-alpha kinase 1
7:6,081,241  USP42 Ubiquitin-specific peptidase 42
7:6,161,779  CYTH3 Cytohesin 3
7:6,329,411  FAM220A Family with sequence similarity 220, member A
7:6,374,527  RAC1 Rac family small GTPase 1
7:6,409,129  DAGLB Diacylglycerol lipase, beta
7:6,461,089  KDELR2 KDEL endoplasmic reticulum protein retention receptor 2
7:6,496,778  GRID2IP1 GRID2-interacting protein 1
7:6,590,021  INTS15 Integrator complex subunit 15
7:6,688,433  ZNF12 Zinc finger protein-12 (KOX3)
7:7,157,377  C1GALT1 Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
7:7,200,001  LOC105375159 Long intergenic noncoding RNA AC011288.2
7:7,200,001  MDDC Macular dystrophy, dominant cystoid
7:7,200,001  LOC105375159 Long intergenic noncoding RNA AC011288.2
7:7,200,001  MDDC Macular dystrophy, dominant cystoid
7:7,338,194  COL28A1 Collagen, type XXVIII, alpha-1 polypeptide
7:7,566,884  MIOS Missing oocyte/meiosis regulator, Drosophila, homolog of
7:7,636,518  RPA3 Replication protein A3, 14kD
7:7,968,796  GLCCI1 Glucocorticoid-induced transcript 1
7:8,113,184  ICA1 Islet cell autoantigen 1, 69kD
7:8,433,609  NXPH1 Neurexophilin 1
7:10,931,943  COXFA4 Cytochrome c oxidase subunit FA4
7:10,973,872  PHF14 PHD finger protein 14
7:11,370,365  THSD7A Thrombospondin type-1 domain-containing protein 7A
7:12,211,294  TMEM106B Transmembrane protein 106B
7:12,570,720  SCIN Scinderin
7:12,686,903  ARL4A ADP ribosylation factor-like GTPase 4A
7:13,700,001  EDSS2 Ectodermal dysplasia-syndactyly syndrome 2
7:13,891,229  ETV1 ETS variant transcription factor 1
7:13,891,229  ETV1 ETS variant transcription factor 1
7:14,145,049  DGKB Diacylglycerol kinase, beta, 90kD
7:15,117,223  AGMO Alkylglycerol monooxygenase
7:15,611,212  MEOX2 Mesenchyme homeobox 2
7:16,087,525  CRPPA CDP-L-ribitol pyrophosphorylase A
7:16,461,481  SOSTDC1 Sclerostin domain-containing protein 1
7:16,646,181  BZW2 Basic leucine zipper domain- and W2 domain-containing protein 2
7:16,753,755  TSPAN13 Tetraspanin 13
7:16,791,811  AGR2 Anterior gradient 2, protein disulphide isomerase family member
7:16,854,681  AGR3 Anterior gradient 3, Xenopus, homolog of
7:17,298,652  AHR Aryl hydrocarbon receptor
7:17,790,761  SNX13 Sorting nexin 13
7:18,026,770  PRPS1L1 Phosphoribosylpyrophosphate synthetase 1-like 1
7:18,086,825  HDAC9 Histone deacetylase 9
7:19,113,047  TWIST1 TWIST, Drosophila, homolog of, 1
7:19,144,782  FERD3L FER3-like bHLH transcription factor
7:19,695,461  POLR1F Polymerase I, RNA, subunit F
7:20,134,655  MACC1 MET transcriptional regulator MACC1
7:20,329,766  ITGB8 Integrin, beta-8
7:20,615,667  ABCB5 ATP-binding cassette, subfamily B, member 5
7:20,782,279  SP8, BTD Transcription factor Sp8
7:20,900,001  FGQTL2 Fasting plasma glucose level QTL 2; Birth weight QTL 1
7:20,900,001  MYCLK1 Avian myelocytomatosis viral (v-myc) oncogene homolog like 1
7:20,900,001  ASRT2 Asthma-related traits, susceptibilty to, 2
7:20,900,001  MYP17 Myopia 17
7:20,900,001  STQTL17 Stature quantitative trait locus 17
7:21,428,083  SP4 Sp4 transcription factor
7:21,543,039  DNAH11 Dynein, axonemal, heavy chain-11
7:21,900,899  CDCA7L Cell division cycle-associated protein 7-like
7:22,118,236  RAPGEF5 RAP guanine nucleotide exchange factor 5
7:22,727,200  IL6 Interleukin-6 (interferon, beta-2)
7:22,812,974  TOMM7 Translocase of outer mitochondrial membrane 7
7:22,895,843  HYCC1 Hyccin, PI4KA lipid kinase complex, subunit 1
7:23,105,785  KLHL7 Kelch-like 7
7:23,182,048  NUP42 Nucleoporin 42
7:23,246,775  GPNMB Glycoprotein NMB
7:23,299,339  MALSU1 Mitochondrial assembly of ribosomal large subunit 1
7:23,310,209  IGF2BP3 Insulin-like growth factor 2 mRNA-binding protein 3
7:23,504,780  TRA2A Transformer 2 alpha homolog
7:23,710,082  STK31 Serine/threonine kinase 31
7:24,284,190  NPY Neuropeptide Y
7:24,573,452  MPP6 Membrane protein, palmitoylated 6
7:24,698,355  GSDME Gasdermin E
7:24,796,537  OSBPL3 Oxysterol-binding protein-like protein 3
7:25,118,656  CYCS Cytochrome C, somatic
7:25,125,772  C7orf31 Chromosome 7 open reading frame 31
7:25,224,570  NPVF Neuropeptide VF precursor
7:25,949,919  MIR148A Micro RNA 148A
7:26,152,198  NFE2L3 Nuclear factor erythroid 2-like 3
7:26,189,927  HNRNPA2B1 Heterogeneous nuclear ribonucleoprotein A2/B1
7:26,201,443  CBX3 Chromobox homolog 3
7:26,291,862  SNX10 Sorting nexin 10
7:26,654,770  SKAP2 src kinase associated phosphoprotein 2
7:27,092,993  HOXA1 Homeobox A1
7:27,100,354  HOXA2 Homeobox A2
7:27,107,010  HOXA3 Homeobox-A3
7:27,121,919  HOXAAS2 HOXA cluster antisense RNA 2
7:27,128,525  HOXA4 Homeobox-A4
7:27,140,364  HOXAAS3 HOXA cluster antisense RNA 3, noncoding
7:27,141,052  HOXA5 Homeobox A5
7:27,145,396  HOXA6 Homeobox A6
7:27,153,716  HOXA7 Homeobox A7
7:27,162,438  HOXA9 Homeobox A9
7:27,169,480  MIR196B Micro RNA 196B
7:27,170,605  HOXA10 Homeobox A10
7:27,181,157  HOXA11 Homeobox A11
7:27,185,408  HOXA11AS Homeobox A11, antisense
7:27,194,364  HOXA13 Homeobox A13
7:27,200,421  HOTTIP HOXA distal transcript antisense RNA
7:27,242,802  EVX1 Even-skipped homeobox 1
7:27,525,442  HIBADH 3-hydroxyisobutyrate dehydrogenase
7:27,739,373  TAX1BP1 TAX1-binding protein 1
7:27,830,577  JAZF1 JAZF zinc finger 1
7:28,299,321  CREB5 cAMP response element-binding protein 5
7:28,800,001  HHT4 Telangiectasia, hereditary hemorrhagic, type 4
7:28,953,358  TRIL TLR4 interactor with leucine-rich repeats
7:28,994,636  CPVL Carboxypeptidase, vitellogenic-like
7:29,146,591  CHN2 Chimerin 2 (GTPase-activating protein, rho, 3)
7:29,563,835  PRR15 Proline-rich protein 15
7:29,806,508  WIPF3 WAS/WASL-interacting protein family, member 3
7:29,920,103  SCRN1 Secernin 1
7:30,005,923  FKBP14 FK506-binding protein 14
7:30,028,412  FAPP2 Phosphatidylinositol 4-phosphate adaptor protein 2
7:30,134,986  MTURN Maturin, neural protenitor differentiation regulator homolog
7:30,284,597  ZNRF2 Zinc finger and ring finger protein 2
7:30,424,527  NOD1 Nucleotide-binding oligomerization domain protein 1
7:30,496,621  GGCT Gamma-glutamylcyclotransferase
7:30,594,735  GARS1 Glycyl-tRNA synthetase 1
7:30,651,942  CRHR2 Corticotropin releasing hormone receptor-2
7:30,752,135  INMT Indolethylamine N-methyltransferase
7:30,911,853  AQP1 Aquaporin-1 (channel-forming integral protein, 28kD)
7:30,963,953  GHRHR Growth hormone releasing hormone receptor
7:31,052,308  ADCYAP1R1 ADCYAP receptor, type I
7:31,337,465  NEUROD6 Neurogenic differentiation 6
7:31,616,777  PDE1C Phosphodiesterase 1C
7:31,687,215  GSBS G-substrate
7:32,485,338  LSM5 LSM5 protein
7:32,495,489  AVL9 AVL9 cell migration-associated protein
7:32,868,172  KBTBD2 Kelch repeat- and BTB domain-containing protein 2
7:32,957,440  FKBP9 FK506-binding protein 9
7:33,014,113  NT5C3A 5′ nucleotidase, cytosolic IIIA (uridine 5′ monophosphate hydrolase 1)
7:33,094,797  RP9 RP9 pre-mRNA splicing factor
7:33,129,285  PTHB1 Parathyroid hormone-responsive B1 gene
7:33,904,915  BMPER BMP binding endothelial regulator
7:34,346,512  NPSRAS1 NPSR1 antisense RNA 1
7:34,658,218  NPSR1 Neuropeptide S receptor 1
7:34,928,881  DPY19L1 DPY19-like 1
7:35,202,430  TBX20 T-box 20
7:35,632,659  HERPUD2 HERPUD family member 2
7:35,800,986  SEPTIN7.. Septin 7
7:36,153,254  EEPD1, Endonuclease/exonuclease/phosphatase family domain-containing protein 1
7:36,324,152  MATCAP2 Microtubule-associated tyrosine carboxypeptidase 2
7:36,389,862  ANLN Actin-binding protein anillin
7:36,512,941  AOAH Acyloxyacyl hydrolase (neutrophil)
7:36,852,906  ELMO1 Engulfment and cell motility gene 1
7:37,100,001  TRGJ@ T-cell receptor gamma chain joining gene cluster
7:37,683,766  GPR141 G protein -coupled receptor 141
7:37,848,597  NME8 NME/NM23 family member 8
7:37,905,932  SFRP4 Secreted frizzled-related protein 4
7:37,920,640  EPDR1 Ependymin-related protein 1
7:38,178,245  STARD3NL STARD3 N-terminal like
7:38,240,024  TRGC2 T-cell receptor gamma chain constant region 2
7:38,259,643  TARP T-cell antigen receptor, gamma subunit, alternate reading frame protein
7:38,260,088  TRGC1 T-cell receptor gamma chain constant region 1
7:38,383,704  AMPH Amphiphysin
7:38,722,974  VPS41 VPS41 subunit of HOPS complex
7:38,977,909  POU6F2 POU domain, class 6, transcription factor 2
7:39,623,572  RALA RAS-like protooncogene A
7:39,950,256  CDK13 Cyclin-dependent kinase 13
7:40,126,027  MPLKIP M-phase specific PLK1 interacting protein
7:40,135,005  SUGCT Succinyl-CoA:glutarate-CoA transferase
7:41,685,114  INHBA Inhibin, beta-1
7:41,960,949  GLI3 GLI-Kruppel family member GLI3 (oncogene GLI3)
7:42,916,861  PSMA2 Proteasome (prosome, macropain) subunit, alpha type, 2
7:42,932,376  MRPL32 Mitochondrial ribosomal protein L32
7:43,112,647  HECW1 HECT, C2, and WW domains-containing E3 ubiquitin-protein ligase 1
7:43,300,001  SLERT Box H/ACA small nucleolar RNA long noncoding RNA  enhances pre-rRNA 
7:43,300,001  SRS2 Silver-Russell syndrome
7:43,508,728  LUARIS Long noncoding RNA upregulator of antiviral response interferon signaling
7:43,583,108  STK17A Serine/threonine protein kinase 17A
7:43,608,457  COA1 Cytochrome c oxidase assembly factor 1 homolog
7:43,758,122  BLVRA Biliverdin reductase A
7:43,866,558  MRPS24 Mitochondrial ribosomal protein S24
7:43,875,913  URGCP Upregulator of cell proliferation
7:43,997,897  SPDYE1 Speedy/RINGO cell cycle regulator family, member E1
7:44,044,702  DBNL Drebrin-like
7:44,062,727  PGAM2 Phosphoglycerate mutase, muscle form
7:44,072,062  POLM Polymerase, DNA, mu
7:44,104,345  AEBP1 AE-binding protein 1
7:44,114,680  POLD2 Polymerase (DNA directed), delta 2, regulatory subunit, 50kD
7:44,138,864  MYL7 Myosin, light chain 7, regulatory
7:44,143,213  GCK Glucokinase (hexokinase-4)
7:44,200,978  YKT6 YKT6 v-SNARE homolog
7:44,217,154  CAMK2B Calcium/calmodulin-dependent protein kinase II-beta
7:44,379,119  NUDCD3 NUDC domain-containing protein 3
7:44,512,535  NPC1L1 NPC1-like intracellular cholesterol transporter 1
7:44,565,804  DDX56 DEAD-box helicase 56
7:44,577,894  TMED4 Transmembrane p24 trafficking protein 4
7:44,606,627  OGDH Oxoglutarate dehydrogenase, lipoamide 
7:44,748,571  ZMIZ2 Zinc finger MIZ-domain containing 2
7:44,748,571  ZMIZ2 Zinc finger MIZ-domain containing 2
7:44,796,681  PPIA Peptidylprolyl isomerase A (cyclophilin A)
7:44,826,889  H2AZ2 H2A.Z variant histone 2
7:44,826,889  H2AZ2 H2A.Z variant histone 2
7:44,876,299  PURB Purine-rich element-binding protein B
7:44,962,662  MYO1G Myosin IG
7:44,999,746  CCM2 CCM2 scaffold protein
7:45,080,437  NACAD NAC-alpha domain-containing protein
7:45,100,100  TBRG4 Transforming growth factor-beta regulator 4
7:45,104,906  SNORA5C Small nucleolar RNA, H/ACA box, 5C
7:45,157,791  RAMP3 Receptor activity-modifying protein 3
7:45,400,001  TTIM1 T-cell tumor invasion and metastasis-1 
7:45,574,140  ADCY1 Adenylate cyclase-1, brain
7:45,723,787  SEPTIN13.. Septin 13
7:45,888,488  IGFBP1 Insulin-like growth factor-binding protein-1
7:45,912,245  IGFBP3 Insulin-like growth factor-binding protein-3
7:47,275,154  TNS3 Tensin 3
7:47,774,614  PKD1L1 Polycystin 1L1
7:47,963,288  HUS1 HUS1 checkpoint clamp component
7:47,987,148  SUN3 SAD1 and UNC84 domain-containing protein 3
7:48,088,704  UPP1 Uridine phosphorylase 1
7:48,171,458  ABCA13 ATP-binding cassette, subfamily A, member 13
7:49,000,001  ALL2 Leukemia, acute lymphoblastic, susceptibility to, 2
7:49,773,638  VWC2 von Willebrand factor C domain-containing protein 2
7:49,840,654  ZPBP Zona pellucida-binding protein
7:50,303,455  IKZF1 Ikaros family zinc finger 1
7:50,444,133  FIGNL1 Fidgetin-like protein 1
7:50,458,442  DDC DOPA decarboxylase (aromatic L-amino acid decarboxylase)
7:50,500,001  CMH21 Cardiomyopathy, familial hypertrophic, 21
7:50,590,068  GRB10 Growth factor receptor-bound protein-10
7:51,016,212  COBL Cordon-bleu, mouse, homolog of
7:53,900,001  HPC4 Prostate cancer, hereditary, 4
7:53,900,001  NYS3 Nystagmus 3, congenital, autosomal dominant
7:54,752,253  SEC61G SEC61 translocon, gamma subunit
7:55,019,017  EGFR Epidermal growth factor receptor
7:55,238,436  ELDR EGFR long noncoding downstream RNA
7:55,365,337  LANCL2 LanC-like 2
7:55,434,964  VOPP1 Vesicular, overexpressed in cancer, prosurvival protein 1
7:55,764,797  PSPHP1 Phosphoserine phosphatase pseudogene 1
7:55,793,540  SEPTIN14.. Septin 14
7:55,887,456  ZNF713 Zinc finger protein 713
7:55,951,877  MRPS17 Mitochondrial ribosomal protein S17
7:55,964,585  NIPSNAP2 Nipsnap homolog 2
7:56,011,064  PSPH Phosphoserine phosphatase
7:56,051,765  CCT6A Chaperonin containing T-complex polypeptide 1, subunit 6A
7:56,064,286  SUMF2 Sulfatase-modifying factor 2
7:56,080,295  PHKG1 Phosphorylase kinase, gamma 1, muscle
7:56,101,573  CHCHD2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2
7:57,117,676  ZNF479 Zinc finger protein 479
7:60,100,001  HRX Hyperreflexia
7:62,100,001  ANIB1 Aneurysm, intracranial berry, 1
7:62,100,001  EEC1 Ectrodactyly, ectodermal dysplasia, cleft lip/palate, 1
7:62,100,001  EOE1 Esophagitis, eosinophilic, 1
7:64,666,133  ZNF107 Zinc finger protein-107
7:64,794,428  ZNF138 Zinc finger protein-138
7:64,877,603  ZNF273 Zinc finger protein 273
7:64,971,772  ZNF117 Zinc finger protein-117
7:64,990,356  ERV3 Endogenous retroviral sequence-3 (includes zinc finger protein H-plk)
7:65,373,855  ZNF92 Zinc finger protein-92
7:65,865,772  VKORC1L1 Vitamin K epoxide reductase complex, subunit 1-like 1


 

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