Here I present: “Clostridium perfringens enterotoxin-receptor”, Victor McKusick, Mendelian Inheritance in Man’, 1966. 腸毒素受體。icd10=B96.7
INTRODUCTION.
Clostridium enterotoxins are toxin produced by Clostridium species. Clostridium species are one of the major causes of food poisoning/gastrointestinal illness. They are anaerobic gram-positive, spore-forming rods that occur naturally in the soil. Among the family are: Clostridium botulinum, which produces one of the most potent toxins in existence; Clostridium tetani, causative agent of tetanus; and Clostridium perfringens, commonly found in wound infections and diarrhea cases.
There is evidence that the Clostridium enterotoxin-receptor is the claudin-3 (CLDN3) gene protein on cytogenetic location 7q11.23 and genomic coordinates 7:73,768,997-73,770,270. The screenshot of the CLDN3 gene 1,274 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides CLDN3 in the 7q11.23 cytogenetic location are listed BENEATH.
| Coordinate | Symbol | Genomic Name |
| 7:73,683,597 | BUD23 | rRNA methyltransferase and ribosome maturation factor Bud23 |
| 7:73,699,210 | STX1A | Syntaxin 1A, brain |
| 7:73,735,069 | WBSCR26 | Williams-Beuren syndrome chromosome region 26 |
| 7:73,736,094 | ABHD11 | Abhydrolase domain-containing protein 11 |
| 7:73,768,997 | CLDN3 | Claudin-3 (Clostridium perfringens enterotoxin receptor 2) |
| 7:73,830,996 | CLDN4 | Claudin 4 |
| 7:73,834,590 | WBSCR27 | Williams-Beuren syndrome chromosome region 27 |
| 7:73,860,848 | WBSCR28 | Williams-Beuren syndrome chromosome region 28 |
| 7:74,028,173 | ELN | Elastin |
| 7:74,083,804 | LIMK1 | LIM domain kinase 1 |
