Here I present: “Coronary Artery Disease”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (CAD) 冠狀動脈疾病。icd10=I25
INTRODUCTION.
CD36 is a fatty acid translocase (FAT) that transports long-chain fatty-acids (LCFA) and cholesterol across the plasma membrane (PM).
There is evidence a common haplotype in the CD36 gene on cytogenetic location 7q21.11 and genomic coordinates 7:80,602,207-80,679,274 is associated with high free fatty acid levels and increased risk of coronary artery disease (CAD).
The screenshot of the CD36 gene 77,068 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides CD36 in cytogenetic location 7q21.11 are listed BENEATH.
| Coordinate | Symbol | Genomic Name |
| 7:77,900,001 | STQTL11 | Stature quantitative trait locus 11 |
| 7:78,017,055 | MAGI2 | Membrane-associated guanylate kinase, WW and PDZ domains-containing, 2 |
| 7:80,134,831 | GNAI1 | Guanine nucleotide-binding protein alpha-inhibiting activity polypeptide-1 |
| 7:80,458,635 | GNAT3 | Guanine nucleotide-binding protein, alpha-transducing activity polypeptide 3 |
| 7:80,602,207 | CD36 | CD36 antigen (collagen type I) |
| 7:80,742,538 | SEMA3C | Semaphorin 3C |
| 7:81,699,010 | HGF | Hepatic growth factor |
| 7:81,946,444 | CACNA2D1 | Calcium channel, voltage-dependent, alpha-2/delta subunit |
| 7:82,754,012 | PCLO | Piccolo, mouse, homolog of |
| 7:83,363,238 | SEMA3E | Semaphorin 3E |
