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“Tuberculosis”, Victor McKusick, Mendelian Inheritance in Man, 1966. (TB) 結核病。icd10=A15

 


Here I present: “Tuberculosis”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (TB) 結核病。icd10=A15

INTRODUCTION.

There is evidence susceptibility to Mycobacterium tuberculosis (TB) is associated with variation in many genes including interferon-gamma receptor type-1 (IFNGR1) on cytogenetic location 6q23.3 and genomic coordinates 6:137,197,484-137,219,385.  The screenshot of the IFNGR1 gene 21,902 bp (base pairs) of DNA sequence length is shown BELOW.  Nine (9) other genes besides IFNGR1 in the 6q23.3 cytogenetic location are listed BENEATH.

 






 

 

 

Coordinate  Symbol  Genomic Name
6:136,822,592  PEX7 Peroxisomal biogenesis factor-7
6:136,922,301  SLC35D3 Solute carrier family 35, member D3
6:136,999,971  IL20RA Interleukin 20 receptor, alpha
6:137,143,820  IL22BP Interleukin 22-binding protein
6:137,197,484  IFNGR1 Immune interferon, receptor for
6:137,492,199  OLIG3 Oligodendrocyte lineage transcription factor 3
6:137,823,669  WAKMAR2 Wound- and keratinocyte migration-associated RNA 2
6:137,866,349  TNFAIP3 Tumor necrosis factor-alpha-induced protein 3
6:138,088,505  PERP p53 effector related to PMP22
6:138,161,939  ARFGEF3 ADP-ribosylation factor guanine exchange factor 3

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