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“Dyslexia”, Victor McKusick, Mendelian Inheritance in Man, 1966. (DYX2) icd10=F81. 0

Here I present: “Dyslexia”, Victor McKusick, Mendelian Inheritance in Man’, 1966. (DYX2) icd10=F81. 0

INTRODUCTION.

Dyslexia (DYX) is a disorder manifested by difficulty learning to read despite conventional instruction, adequate intelligence, and sociocultural opportunity. It is among the most common neurodevelopmental disorders, with a prevalence of 5 to 12%.

 

There is evidence that dyslexia type-2 is caused by mutation in the DYX2 gene on cytogenetic location 6p22-p21 and genomic coordinates 6:15,200,001-46,200,000. The screenshot of the DYX2 gene 31,000,000 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides DYX2 in the 6p22-p21 cytogenetic location are listed BENEATH.

 





 

Coordinate  Symbol  Genomic Name
6:15,200,001  ALPQTL3 Alkaline phosphatase, plasma level of, QTL 3
6:15,200,001  BWQTL4 Birth weight quantitative trait locus 4
6:15,200,001  CIHL Hearing loss, cisplatin-induced, susceptibility to
6:15,200,001  CMAHP Cytidine monophospho-N-acetylneuraminic acid hydroxylase 
6:15,200,001  DYX2 Dyslexia, susceptibility to, 2
6:15,200,001  NBLST4 Neuroblastoma, susceptibility to, 4
6:15,200,001  OTSC3 Otosclerosis 3
6:15,246,069  JARID2 Jumonji and AT-rich interaction domain containing 2
6:15,522,807  DTNBP1 Dystrobrevin-binding protein 1 (dysbindin)
6:16,129,086  MYLIP Myosin regulatory light chain-interacting protein

 

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