Here I present: “Schizophrenia”, Victor McKusick, Mendelian Inheritance in Man’, 1966.
INTRODUCTION.
Schizophrenia is a mental disorder characterized by hallucinations’ (typically hearing voices), delusions, disorganized thinking and behavior and flat or inappropriate affect. Symptoms develop gradually and typically begin during young adulthood and are never resolved.
There is evidence that Schizophrenia type-12 is caused by a mutation in the SCZD12 gene on cytogenetic location 1p36.2 and genomic coordinates 1:7,100,001-15,900,000 . The screenshot of the SCZD12 gene 8,800,000 bp (base pairs) of DNA sequence length is shown BELOW. Nine (9) other genes besides SCZD12 in the 1p36.2 cytogenetic location are listed BENEATH.
| Coordinate | Symbol | Genomic Name. |
| 1:6,624,868 | THAP3 | THAP domain-containing protein 3 |
| 1:6,634,170 | DNAJC11 | DNAJ/HSP40 homolog, subfamily C, 11 |
| 1:6,785,454 | CAMTA1 | Calmodulin-binding transcription activator 1 |
| 1:7,100,001 | GLC3B | Glaucoma 3, primary infantile, B |
| 1:7,100,001 | SCZD12 | Schizophrenia 12 |
| 1:7,771,296 | VAMP3 | Vesicle-associated membrane protein 3 |
| 1:7,784,291 | PER3 | Period circadian regulator 3 |
| 1:7,847,612 | UTS2 | Urotensin II |
| 1:7,915,871 | TNFRSF9 | Tumor necrosis factor receptor superfamily, 9 |
| 1:7,961,711 | DJ1 | Oncogene DJ-1 |
