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“Gelatinous Drop-like Corneal Dystrophy (GDCD)”, Victor McKusick, “Mendelian Inheritance in Man”, 1966.

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ABOVE is the twenty-four (24) hour day of  CHROMOSOMIC CLOCK and this time is one (#1).

Here I present: Gelatinous Drop-like Corneal Dystrophy (GDCD)”, Victor McKusick, Mendelian Inheritance in Man’, 1966.  Familial subepithelial corneal amyloidosis (FSCA), is an alternate term for gelatinous drop-like corneal dystrophy (GDCD).

INTRODUCTION.

Gelatinous drop-like corneal dystrophy (GDCD) is a form of superficial corneal dystrophy characterized by multiple prominent milky-white gelatinous nodules beneath the corneal epithelium and marked visual impairment.  A number of mutations causing this disease have been described in the gene encoding Tumor-associated calcium signal transducer 2 (TACSTD2).  The TACSTD2 gene is on cytogenetic location  1p32.1  and genomic coordinates  1:58,575,433-58,577,252 .  The screenshot of the TACSTD2 gene is shown BELOW of the 1,820 bp (base pairs) of DNA sequence length.

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